Publications
Adapting to change: insights from new organisms in cell and developmental biology
Steffen Lemke, Ashley Albright, Annika Guse
Development, Oct 2024, https://doi.org/10.1242/dev.204389
The cellular basis of feeding-dependent body size plasticity in sea anemones
Garschall, K., Pascual-Carreras, E., García-Pascual, B., Filimonova, D., Guse, A., Johnston, I.G., Steinmetz, P.R.H.
Development, Oct 2024, https://doi.org/10.1242/dev.202926
Linking cell biology and ecology to understand coral symbiosis evolution
Niels J. Dingemanse, Annika Guse
PLOS Biology, April 2024, https://doi.org/10.1371/journal.pbio.3002593
Negative phototaxis in the photosymbiotic sea anemone Aiptasia as a potential strategy to protect symbionts from photodamage
Kishimoto, M., Gornik, S.G., Foulkes, N.S., Guse, A.
Scientific Reports, Oct 2023, https://www.nature.com/articles/s41598-023-44583-9
Unlocking the Complex Cell Biology of Coral-Dinoflagellate Symbiosis: A Model Systems Approach
Jacobovitz, M.R., Hambleton, E. A., Guse, A.
Annual Review of Genetics, 2023 Sep, doi:10.1146/annurev-genet-072320-125436
A predatory gastrula leads to symbiosis-independent settlement in Aiptasia
Maegele, I., Rupp, S., Özbek, S., Guse, A., Hambleton, E. A., Holstein, T.W.
PNAS, 2023 Sep, doi:10.1073/pnas.2311872120
Host nutrient sensing is mediated by mTOR signaling in cnidarian-dinoflagellate symbiosis
Voss, P.A., Gornik, S.G., Jacobovitz, M.R., Rupp, S., Dörr, M., Maegele, I., Guse, A.
Current Biology, 2023 Sep, doi:10.1016/j.cub.2023.07.038
Nuclear transformation of a dinoflagellate symbiont of corals
Gornik, S.G., Maegele, I., Hambleton, E.A., Voss, P.A., Ross F. Waller, R.F. and Guse, A.
Frontiers in Marine Science, 2022 Nov, doi:10.3389/fmars.2022.1035413
Dinoflagellate symbionts escape vomocytosis by host cell immune suppression
Jacobovitz, M.R.*, Rupp, S.*, Voss, P.A., Maegele, I., Gornik, S.G, Guse, A. (*equal contribution)
Nature Microbiology, 2021 Apr, doi:10.1038/s41564-021-00897-w Full text access (pdf)
Photoreceptor diversification accompanies the evolution of Anthozoa
Gornik, S.G., Bergheim, B.G., Morel, B., Stamatakis, A., Foulkes, N.S., Guse, A.
Molecular Biology and Evolution, 2020 Nov, doi:/10.1093/molbev/msaa304
Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis
Hambleton, E.A., Jones, V.A.S., Maegele, I., Kvaskoff, D. Sachsenheimer, T., Guse, A.
eLife, 2019 Jun, 10.7554/eLife.43923
Microinjection to deliver protein, mRNA and DNA into zygotes of thecnidarian endosymbiosis model
Aiptasia sp.
Jones, V.A.S.*, Bucher, M.*, Hambleton, E.A., Guse, A.
Scientific Reports, 2018 Nov, doi:10.1038/s41598-018-34773-1
Aiptasia sp. larvae as a model to reveal mechanisms of symbiont selection in cnidarians.
Wolfowicz, I., *Baumgarten, S.,*Voss, P.A., Hambleton, E.A., Voolstra, C.R., Hatta, M., Guse, A.
Scientific Reports, 2016 Sep, doi:10.1038/srep32366
Development and symbiosis establishment in the cnidarian endosymbiosis model Aiptasia sp..
Bucher, M., Wolfowicz, I., Voss, P.A., Hambleton, E.A., Bucher, M., Guse, A.
Scientific Reports, 2016 Jan, doi:10.1038/srep19867
Induction of gametogenesis in the cnidarian endosymbiosis model Aiptasia sp..
Grawunder, D.*, Hambleton, E.A.*, Bucher, M., Wolfowicz, I., Bechtoldt, N., Guse, A.
Scientific Reports, 2015 Oct, doi:10.1038/srep15677
The genome of Aiptasia, a sea anemone model for coral symbiosis.
Baumgarten, S., Simakov, O., Esherick, L.Y., Liew,Y.J., Lehnert,E.M., Michell, C.T, Li, Y., Hambleton, E.A, Guse, A., Oates, M.E., Gough, J., Weis, V.M., Aranda, M., Pringle, J.R., Voolstra, C.R.
PNAS, 2015 Aug, 11893–11898, doi: 10.1073/pnas.1513318112
Similar specificities of symbiont uptake by adults and larvae in an anemone model system for coral biology.
Hambleton, E.A.*, Guse, A.*, Pringle, J.R.
Journal of Experimental Biology, 2014 May 1;217 (1613-1619)
[PMID: 24526722]
CENP-A confers a reduction in height on octameric nucleosomes.
Miell, M.D.D, Fuller, C.J., Guse, A., Barysz, H.M., Downes, A., Owen-Hughes, T., Rappsilber, J., Straight, A.F., Allshire, R.C.
Nature Structure & Molecular Biology, 2013 Jun;20(6):763-5
[PMID: 23644598]
A cell free system for functional centromere and kinetochore assembly.
Guse, A., Fuller, C.J., Straight, A.F.
Nature Protocols 2012 Sep 20;7 (1847-1869)
[PMID: 23018190]
In vitro centromere and kinetochore assembly on defined chromatin templates.
Guse, A., Carroll, C.W., Moree, B., Fuller, C.J., Straight, A.F.
Nature 2011 Aug 28;477(7364):354-8
[PMID: 21874020]
Functional knockdown of VCAM-1 at the posttranslational level with ER retained antibodies.
Strebe, N.*, Guse, A.*, Schüngel, M., Schirrmann, T., Hafner, M., Jostock, T., Hust, M., Müller, W., Dübel, S.
Journal of Immunological Methods 2009 Feb 28;341(1-2):30-40
[PMID: 19038261]
Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis.
Guse, A., Mishima, M., Glotzer, M.
Current Biology 2005 Apr 26;15(8):778-86
[PMID: 15854913]
CSC-1: a subunit of the Aurora B kinase complex that binds the survivin-like protein BIR-1 and the incenp-like protein ICP-1.
Romano, A., Guse, A., Krascenicova, I., Schnabel, H., Schnabel, R., Glotzer, M.
Journal of Cell Biology 2003 Apr 28;161(2):229-36
[PMID: 12707312]
Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA.
Guse, A., Stevenson, C.E., Kuper, J., Buchanan, G., Schwarz, G., Giordano, G., Magalon, A.,Mendel, R.R., Lawson, D.M., Palmer, T.
Journal of Biological Chemistry 2003 Jul 11;278(28):25302-7
[PMID: 12719427]
Funding
Current Research
Shedding light on corals: How DNA damage repair, the circadian clock and cryptochromes shape the response of Anthozoa to sunlight
Principal Investigators: Annika Guse & Nicolas Foulkes
Funding Organization: German Research Foundation (DFG)
Project Number: 50844158
Funding: 467.500 €
Previous Projects
Organization and function of the dinoflagellate genome
Principal Investigators: Stephanie Weber, Aaron Straight and Annika Guse
Duration: 2020 - 2022
Funding Organisation: New Frontiers in Research Fund - Exploration
Project Number: NFRFE-2019-00189
Funding: 250.000$
Mensch & Meer: symbiotische Lebensformen verstehen und vermitteln
Principal Investigators: Annika Guse & Nikolas Jaspert
Duration: 01/10/2020 - 31/03/2022
Funding Organisation: Heidelberg University
Grant Type: Marsilius Kolleg Fellows
Funding: 80.000€
Resolving the molecular mechanisms of intracellular coral-algal symbiosis (SYMCELLS)
Principal Investigator: Annika Guse
Duration: 01/06/2017 to 31/05/2022
Funding organization: European Research Council
Project Number: 724715
Funding: 2.270.500€
Cholesterol-binding proteins and dinoflagellate sterols in coral symbiosis
Principal Investigator: Annika Guse
Duration: 01/06/2016 - 31/05/2017
Funding Organization: Boehringer Ingelheim Stiftung
Grant Type: Exploration Grant
Funding: 72.650 €
Molecular Basis of Coral Symbiosis (ESYMBIOSIS)
Principal Investigator: Annika Guse
Duration: 01/05/2014 to 30/04/2018
Funding Organization: European Commission
Project Number: 631740
Funding: 100.000€
Molecular basis of cnidarian endosymbiosis and its response to environmental change
Principal Investigator: Annika Guse
Duration: 01/01/2013 to 31/12/2017
Funding Organization: German Research Foundation (DFG)
Project Number: 221467980
Funding: 1.670.000€